Nucleocapsid protein as early diagnostic marker for SARS

被引:106
作者
Che, XY
Hao, W
Wang, YD
Di, B
Yin, K
Xu, YC
Feng, CS
Wan, ZY
Cheng, VCC
Yuen, KY
机构
[1] First Mil Med Univ, Guangzhou, Peoples R China
[2] Ctr Dis Control & Prevent, Guangzhou, Peoples R China
[3] Univ Hong Kong, Hong Kong Special Adm Reg, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.3201/eid1011.040516
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Serum samples from 317 patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6-10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.
引用
收藏
页码:1947 / 1949
页数:3
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