Mild and efficient molybdenum-mediated Pauson-Khand-type reaction

被引：33

作者：

Adrio, J ^{[1
]}

Rivero, MR ^{[1
]}

Carretero, JC ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 03期

关键词：

D O I：

10.1021/ol047678u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The molybdenum-mediated Pauson-Khand reaction promoted by Mo(CO)(3)(DMF)(3) takes place under very mild conditions in the absence of any promoter. High yields in Pauson-Khand adducts are obtained in the cyclization of a wide variety of functionatized 1,6- and 1,7-enzymes. Enynes bearing electron withdrawing groups at the alkene terminus are particularly good substrates.

引用

页码：431 / 434

页数：4

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