A review of the current use of magnetic resonance imaging in pregnancy and safety implications for the fetus

被引:201
作者
De Wilde, JP [1 ]
Rivers, AW [1 ]
Price, DL [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Bioengn, Bagrit Ctr, London SW7 2AZ, England
关键词
magnetic resonance imaging; pregnancy; safety; fetus; fetal;
D O I
10.1016/j.pbiomolbio.2004.08.010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This paper presents an overview of the application of and risks of exposure to Magnetic Resonance Imaging (MRI) in pregnancy. It reviews the risks to the fetus by considering the hazards in terms of the three main components of an MRI system. These are the static magnetic field. the time-varying magnetic gradient fields and the pulsed radio frequency fields. The hazards discussed are biological effects. miscarriage, heating effects and acoustic noise exposure. This paper also presents a survey of MRI sites within the United Kingdom to ascertain the extent of MRI usage in pregnancy. To validate the situation of MRI in pregnancy a survey was sent to 352 MR units throughout the United Kingdom. The questions were grouped to assess (a) maternal MRI diagnosis (b) fetal MRI and (c) work practices for pregnant MRI staff. The results showed that 91% of sites were imaging pregnant women in need of diagnosis in the second and third trimester. This paper highlights that MRI can add information for fetal central nervous system abnormalities identified by ultrasound screening. however within the UK direct fetal imaging was only performed in 8% of sites. This paper indicates the need for research to be undertaken for specific MRI clinical conditions. It also advises that risk assessment for pregnant staff working in MRI is performed. and that there is a clear need for further research into the effects of MRI in pregnancy as there is a need for clear authoritive advice. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:335 / 353
页数:19
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