In vitro activity of nine antifungal agents against clinical isolates of Aspergillus calidoustus

被引:38
作者
Alastruey-Izquierdo, Ana [1 ]
Cuesta, Isabel [1 ]
Houbrakent, Jos [2 ]
Cuenca-Estrella, Manuel [1 ]
Monzon, Araceli [1 ]
Rodriguez-Tudela, Juan L. [1 ]
机构
[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Madrid 28220, Spain
[2] CBS Fungal Biodivers Ctr, Utrecht, Netherlands
关键词
Aspergillus calidoustus; antifungal susceptibility profile; beta tubulin; HEMATOPOIETIC STEM-CELL; FILAMENTOUS FUNGI; TRANSPLANT RECIPIENTS; INOCULUM PREPARATION; USTUS INFECTION; SP NOV; VORICONAZOLE; CASPOFUNGIN; FUMIGATUS;
D O I
10.3109/13693780902803040
中图分类号
R51 [传染病];
学科分类号
100201 [内科学];
摘要
This study analyzes Aspergillus isolates from the Spanish National Centre for Microbiology collection, which were identified morphologically as members of Aspergillus section Usti. Strains were identified through the analysis of the Internal Transcribed Spacer regions and partial tubulin gene sequences. One Aspergillus pseudodeflectus isolate and eight Aspergillus calidoustus isolates were detected in this panel of clinical strains. Terbinafine and the echinocandins micafungin and anidulafungin, were the drugs most active against these species.
引用
收藏
页码:97 / 102
页数:6
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