Chemical Nanosensors Based on Composite Molecularly Imprinted Polymer Particles and Surface-Enhanced Raman Scattering

被引:87
作者
Bompart, Marc [2 ]
De Wilde, Yannick [1 ]
Haupt, Karsten [2 ]
机构
[1] ESPCI ParisTech, Inst Langevin, Lab Opt Phys, CNRS,UMR 7587, F-75231 Paris 05, France
[2] Univ Technol Compiegne, CNRS, UMR 6022, F-60205 Compiegne, France
关键词
GOLD NANOPARTICLES; SILVER ELECTRODE; SPECTROSCOPY; PYRIDINE; SITES; SERS;
D O I
10.1002/adma.200904442
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemical nanosensors with a submicrometer core-shell composite design, based on a polymer core, a molecularly imprinted polymer (MIP) shell for specific analyte recognition, and an interlayer of gold nanoparticles for signal amplification, are described. SERS measurements on single nanosensors yield detection limits of 10(-7) M for the beta-blocker propranolol, several orders of magnitude lower than on plain MIP spheres.
引用
收藏
页码:2343 / 2348
页数:6
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