Slit diaphragm junctional complex and regulation of the cytoskeleton

被引:26
作者
Garg, Puneet [1 ]
Verma, Rakesh [1 ]
Holzman, Lawrence B. [1 ]
机构
[1] Univ Michigan, Sch Med, Dept Vet Affairs, Div Nephrol, Ann Arbor, MI 48109 USA
来源
NEPHRON EXPERIMENTAL NEPHROLOGY | 2007年 / 106卷 / 02期
关键词
podocyte; nephrin; Neph1; actin cytoskeleton; Nck;
D O I
10.1159/000101795
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
In recent years, identification of proteins found at the slit diaphragm has greatly improved our understanding of the molecular mechanisms responsible for forming and maintaining the glomerular filtration barrier. This review examines the function of proteins identified at the podocyte intercellular junction in coordinating podocyte intercellular junction dynamics or cytoskeletal dynamics. Copyright (c) 2007 S. Karger AG, Basel.
引用
收藏
页码:E67 / E72
页数:6
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