Slit diaphragm junctional complex and regulation of the cytoskeleton

被引：26

作者：

Garg, Puneet ^{[1
]}

Verma, Rakesh ^{[1
]}

Holzman, Lawrence B. ^{[1
]}

机构：

[1] Univ Michigan, Sch Med, Dept Vet Affairs, Div Nephrol, Ann Arbor, MI 48109 USA

来源：

NEPHRON EXPERIMENTAL NEPHROLOGY | 2007年 / 106卷 / 02期

关键词：

podocyte; nephrin; Neph1; actin cytoskeleton; Nck;

D O I：

10.1159/000101795

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In recent years, identification of proteins found at the slit diaphragm has greatly improved our understanding of the molecular mechanisms responsible for forming and maintaining the glomerular filtration barrier. This review examines the function of proteins identified at the podocyte intercellular junction in coordinating podocyte intercellular junction dynamics or cytoskeletal dynamics. Copyright (c) 2007 S. Karger AG, Basel.

引用

页码：E67 / E72

页数：6

共 61 条

[41] Cell biology of the glomerular podocyte [J].

Pavenstädt, H ;

Kriz, W ;

Kretzler, M .

PHYSIOLOGICAL REVIEWS, 2003, 83 (01) :253-307

[42] ß-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity [J].

Quack, Ivo ;

Rump, L. Christian ;

Gerket, Peter ;

Walther, Inga ;

Vinke, Tobias ;

Vonend, Oliver ;

Grunwald, Thomas ;

Sellin, Lorenz .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (38) :14110-14115

[43]

REEVES W, 1978, LAB INVEST, V39, P90

[44] TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function [J].

Reiser, J ;

Polu, KR ;

Möller, CC ;

Kenlan, P ;

Altintas, MM ;

Wei, CL ;

Faul, C ;

Herbert, S ;

Villegas, I ;

Avila-Casado, C ;

McGee, M ;

Sugimoto, H ;

Brown, D ;

Kalluri, R ;

Mundel, P ;

Smith, PL ;

Clapham, DE ;

Pollak, MR .

NATURE GENETICS, 2005, 37 (07) :739-744

[45] Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts [J].

Salzer, U ;

Prohaska, R .

BLOOD, 2001, 97 (04) :1141-1143

[46] Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus [J].

Scaplehorn, N ;

Holmström, A ;

Moreau, V ;

Frischknecht, F ;

Reckmann, I ;

Way, M .

CURRENT BIOLOGY, 2002, 12 (09) :740-745

[47] NEPH1 defines a novel family of podocin-interacting proteins [J].

Sellin, L ;

Huber, TB ;

Gerke, P ;

Quack, I ;

Pavenstädt, H ;

Walz, G .

FASEB JOURNAL, 2002, 16 (13) :115-+

[48] The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C-elegans [J].

Shen, K ;

Bargmann, CI .

CELL, 2003, 112 (05) :619-630

[49] Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1 [J].

Shen, K ;

Fetter, RD ;

Bargmann, CI .

CELL, 2004, 116 (06) :869-881

[50] Congenital nephrotic syndrome in mice lacking CD2-associated protein [J].

Shih, NY ;

Li, J ;

Karpitskii, V ;

Nguyen, A ;

Dustin, ML ;

Kanagawa, O ;

Miner, JH ;

Shaw, AS .

SCIENCE, 1999, 286 (5438) :312-315

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