Antimalarial xanthones from Garcinia cowa

被引：82

作者：

Likhitwitayawuid, K ^{[1
]}

Phadungcharoen, T

Krungkrai, J

机构：

[1] Chulalongkorn Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Bangkok 10330, Thailand

[2] Chulalongkorn Univ, Fac Med, Dept Biochem, Bangkok 10330, Thailand

来源：

PLANTA MEDICA | 1998年 / 64卷 / 01期

关键词：

D O I：

10.1055/s-2006-957370

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Five xanthones from the bark of Garcinia cowa, namely 7-O-methylgarcinone E (1), cowanin (2), cowanol (3), cowaxanthone (4), and beta-mangostin (5), were found to possess in vitro antimalarial activity against Plasmodium falciparum with IC50 values ranging from 1.50 to 3.00 mu g/ml. Complete H-1- and C-13-NMR assignments of these compounds are also reported.

引用

页码：70 / 72

页数：3

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