Sirviving cardiac stress -: Cardioprotection mediated by a longevity gene

被引:11
作者
Crow, MT [1 ]
机构
[1] Johns Hopkins Univ, Johns Hopkins Asthma & Allergy Ctr, Dept Med, Div Pulm & Crit Care Med, Baltimore, MD 21224 USA
关键词
cardioprotection; cardiac stress; insulin signaling;
D O I
10.1161/01.RES.0000148666.20729.1c
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:953 / 956
页数:4
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共 21 条
[1]   FoxOs at the crossroads of cellular metabolism, differentiation, and transformation [J].
Accili, D ;
Arden, KC .
CELL, 2004, 117 (04) :421-426
[2]   Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes [J].
Alcendor, RR ;
Kirshenbaum, LA ;
Imai, S ;
Vatner, SF ;
Sadoshima, J .
CIRCULATION RESEARCH, 2004, 95 (10) :971-980
[3]   Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae [J].
Anderson, RM ;
Bitterman, KJ ;
Wood, JG ;
Medvedik, O ;
Sinclair, DA .
NATURE, 2003, 423 (6936) :181-185
[4]   Insulin/IGF-I-signaling pathway:: an evolutionarily conserved mechanism of longevity from yeast to humans [J].
Barbieri, M ;
Bonafè, M ;
Franceschi, C ;
Paolisso, G .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2003, 285 (05) :E1064-E1071
[5]   The Sir2 family of protein deacetylases [J].
Blander, G ;
Guarente, L .
ANNUAL REVIEW OF BIOCHEMISTRY, 2004, 73 :417-435
[6]   Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase [J].
Brunet, A ;
Sweeney, LB ;
Sturgill, JF ;
Chua, KF ;
Greer, PL ;
Lin, YX ;
Tran, H ;
Ross, SE ;
Mostoslavsky, R ;
Cohen, HY ;
Hu, LS ;
Cheng, HL ;
Jedrychowski, MP ;
Gygi, SP ;
Sinclair, DA ;
Alt, FW ;
Greenberg, ME .
SCIENCE, 2004, 303 (5666) :2011-2015
[7]   Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase [J].
Cohen, HY ;
Miller, C ;
Bitterman, KJ ;
Wall, NR ;
Hekking, B ;
Kessler, B ;
Howitz, KT ;
Gorospe, M ;
de Cabo, R ;
Sinclair, DA .
SCIENCE, 2004, 305 (5682) :390-392
[8]   An in vitro model of caloric restriction [J].
de Cabo, R ;
Fürer-Galbán, S ;
Anson, RM ;
Gilman, C ;
Gorospe, M ;
Lane, MA .
EXPERIMENTAL GERONTOLOGY, 2003, 38 (06) :631-639
[9]   PI 3-kinase, Akt and cell survival [J].
Downward, J .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2004, 15 (02) :177-182
[10]   Genetics and the specificity of the aging process [J].
Hekimi, S ;
Guarente, L .
SCIENCE, 2003, 299 (5611) :1351-1354