PlantMetabolomics.org: A Web Portal for Plant Metabolomics Experiments

被引:59
作者
Bais, Preeti [1 ,6 ]
Moon, Stephanie M. [2 ]
He, Kun [7 ]
Leitao, Ricardo [7 ]
Dreher, Kate [7 ]
Walk, Tom [7 ]
Sucaet, Yves [1 ,6 ]
Barkan, Lenore [9 ]
Wohlgemuth, Gert [12 ,13 ]
Roth, Mary R. [11 ]
Wurtele, Eve Syrkin [1 ,4 ]
Dixon, Philip [3 ]
Fiehn, Oliver [12 ,13 ]
Lange, B. Markus [9 ]
Shulaev, Vladimir [8 ]
Sumner, Lloyd W. [10 ]
Welti, Ruth [11 ]
Nikolau, Basil J. [2 ]
Rhee, Seung Y. [7 ]
Dickerson, Julie A. [1 ,5 ]
机构
[1] Iowa State Univ, Bioinformat & Computat Biol Program, Ames, IA 50011 USA
[2] Iowa State Univ, Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA
[3] Iowa State Univ, Dept Stat, Ames, IA 50011 USA
[4] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA
[5] Iowa State Univ, Dept Elect & Comp Engn, Ames, IA 50011 USA
[6] Iowa State Univ, Bioinformat & Computat Biol Lab, Ames, IA 50011 USA
[7] Carnegie Inst Sci, Dept Plant Biol, Stanford, CA 94305 USA
[8] Virginia Polytech Inst & State Univ, Virginia Bioinformat Inst, Blacksburg, VA 24061 USA
[9] Washington State Univ, Inst Biol Chem, Pullman, WA 99164 USA
[10] Samuel Roberts Noble Fdn Inc, Div Plant Biol, Ardmore, OK 73401 USA
[11] Kansas State Univ, Div Biol, Manhattan, KS 66506 USA
[12] Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA
[13] Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA
基金
美国国家科学基金会;
关键词
MINIMUM REPORTING STANDARDS; FUNCTIONAL GENOMICS; DATABASE; ARABIDOPSIS; INFORMATION; BIOLOGY;
D O I
10.1104/pp.109.151027
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
PlantMetabolomics.org (PM) is a web portal and database for exploring, visualizing, and downloading plant metabolomics data. Widespread public access to well-annotated metabolomics datasets is essential for establishing metabolomics as a functional genomics tool. PM integrates metabolomics data generated from different analytical platforms from multiple laboratories along with the key visualization tools such as ratio and error plots. Visualization tools can quickly show how one condition compares to another and which analytical platforms show the largest changes. The database tries to capture a complete annotation of the experiment metadata along with the metabolite abundance databased on the evolving Metabolomics Standards Initiative. PM can be used as a platform for deriving hypotheses by enabling metabolomic comparisons between genetically unique Arabidopsis (Arabidopsis thaliana) populations subjected to different environmental conditions. Each metabolite is linked to relevant experimental data and information from various annotation databases. The portal also provides detailed protocols and tutorials on conducting plant metabolomics experiments to promote metabolomics in the community. PM currently houses Arabidopsis metabolomics data generated by a consortium of laboratories utilizing metabolomics to help elucidate the functions of uncharacterized genes. PM is publicly available at http://www.plantmetabolomics.org.
引用
收藏
页码:1807 / 1816
页数:10
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