Signalling to and from tight junctions

被引:693
作者
Matter, K [1 ]
Balda, MS [1 ]
机构
[1] UCL, Inst Ophthalmol, Div Cell Biol, London, England
基金
英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词
D O I
10.1038/nrm1055
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tight junctions have long been regarded as simple barriers that separate compartments of different compositions, but recent research indicates that different types of signalling proteins and transduction pathways are associated with these junctions. They receive and convert signals from the cell interior to regulate junction assembly and function, and transmit signals to the cell interior to modulate gene expression and cell behaviour.
引用
收藏
页码:225 / 236
页数:12
相关论文
共 123 条
  • [1] Adamson P, 1999, J IMMUNOL, V162, P2964
  • [2] Anderson JM, 2001, NEWS PHYSIOL SCI, V16, P126
  • [3] Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity
    Bachmann, A
    Schneider, M
    Theilenberg, E
    Grawe, F
    Knust, E
    [J]. NATURE, 2001, 414 (6864) : 638 - 643
  • [4] Transmembrane proteins of tight junctions
    Balda, MS
    Matter, K
    [J]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2000, 11 (04) : 281 - 289
  • [5] The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
    Balda, MS
    Matter, K
    [J]. EMBO JOURNAL, 2000, 19 (09) : 2024 - 2033
  • [6] The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
    Balda, MS
    Garrett, MD
    Matter, K
    [J]. JOURNAL OF CELL BIOLOGY, 2003, 160 (03) : 423 - 432
  • [7] ASSEMBLY AND SEALING OF TIGHT JUNCTIONS - POSSIBLE PARTICIPATION OF G-PROTEINS, PHOSPHOLIPASE-C, PROTEIN-KINASE-C AND CALMODULIN
    BALDA, MS
    GONZALEZMARISCAL, L
    CONTRERAS, RG
    MACIASSILVA, M
    TORRESMARQUEZ, ME
    SAINZ, JAG
    CEREIJIDO, M
    [J]. JOURNAL OF MEMBRANE BIOLOGY, 1991, 122 (03) : 193 - 202
  • [8] ASSEMBLY OF THE TIGHT JUNCTION - THE ROLE OF DIACYLGLYCEROL
    BALDA, MS
    GONZALEZMARISCAL, L
    MATTER, K
    CEREIJIDO, M
    ANDERSON, JM
    [J]. JOURNAL OF CELL BIOLOGY, 1993, 123 (02) : 293 - 302
  • [9] DISSECTING TUMOR-CELL INVASION - EPITHELIAL-CELLS ACQUIRE INVASIVE PROPERTIES AFTER THE LOSS OF UVOMORULIN-MEDIATED CELL CELL-ADHESION
    BEHRENS, J
    MAREEL, MM
    VANROY, FM
    BIRCHMEIER, W
    [J]. JOURNAL OF CELL BIOLOGY, 1989, 108 (06) : 2435 - 2447
  • [10] DISSOCIATION OF MADIN-DARBY CANINE KIDNEY EPITHELIAL-CELLS BY THE MONOCLONAL-ANTIBODY ANTI-ARC-1 - MECHANISTIC ASPECTS AND IDENTIFICATION OF THE ANTIGEN AS A COMPONENT RELATED TO UVOMORULIN
    BEHRENS, J
    BIRCHMEIER, W
    GOODMAN, SL
    IMHOF, BA
    [J]. JOURNAL OF CELL BIOLOGY, 1985, 101 (04) : 1307 - 1315