Desymmetrisation of cyclopentadienylsilane by asymmetric cyclopropanation

被引：13

作者：

Allais, F ^{[1
]}

Angelaud, R ^{[1
]}

Camuzat-Dedenis, B ^{[1
]}

Julienne, K ^{[1
]}

Landais, Y ^{[1
]}

机构：

[1] Univ Bordeaux 1, Chim Organ & Organomet Lab, F-33405 Talence, France

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 2003卷 / 06期

关键词：

dienes; silicon; cyclopropanation; carbenoids; copper;

D O I：

10.1002/ejoc.200390157

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Desymmetrisation of silylcyclopenta-2,4-diene was carried out by an asymmetric copper(I)-mediated cyclopropanation. An in-depth investigation with various ligands led to the discovery that the PyBox ligands 10a-c were the most efficient ligands for this transformation and led to the cyclopropane 7a with an ee of up to 72%. Further studies aimed at providing insights into the origin of this enantiocontrol are also provided.

引用

页码：1069 / 1073

页数：5

共 35 条

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