Human Neuroscience and the Aging Mind: at Old Problems A New Look

被引:311
作者
Reuter-Lorenz, Patricia A. [1 ]
Park, Denise C. [2 ]
机构
[1] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA
[2] Univ Texas Dallas, Ctr Vital Longev, Richardson, TX 75083 USA
来源
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES | 2010年 / 65卷 / 04期
关键词
Aging; Plasticity; Cognitive Neuroscience; Imaging; AGE-RELATED-CHANGES; WORKING-MEMORY; BRAIN ACTIVITY; PREFRONTAL FUNCTION; NEURAL MECHANISMS; FUNCTIONAL CONNECTIVITY; COGNITIVE NEUROSCIENCE; DEFAULT NETWORK; WHITE-MATTER; PERFORMANCE;
D O I
10.1093/geronb/gbq035
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
In this article. marking the 65th anniversary of the Journal of we offer a broad-brush overview of the new synthesis between neuroscientific and psychological approaches to cognitive aging. We provide a selective review of brain imaging studies and their relevance to mechanisms of cognitive aging first identified primarily from behavioral measurements. We also examine some new key discoveries. including evidence favoring plasticity and compensation that have emerged specifically from using cognitive neuroscience methods to study healthy aging. We then summarize several recent neurocognitive theories of aging, including our own model the Scaffolding Theory of Aging and Cognition. We close by discussing some newly emerging trends and future research trajectories for investigating the aging in and bram.
引用
收藏
页码:405 / 415
页数:11
相关论文
共 95 条
[41]   An age-related deficit in prefrontal cortical function associated with refreshing information [J].
Johnson, MK ;
Mitchell, KJ ;
Raye, CL ;
Greene, EJ .
PSYCHOLOGICAL SCIENCE, 2004, 15 (02) :127-132
[42]   Age differences in behavior and PET activation reveal differences in interference resolution in verbal working memory [J].
Jonides, J ;
Marshuetz, C ;
Smith, EE ;
Reuter-Lorenz, PA ;
Koeppe, RA ;
Hartley, A .
JOURNAL OF COGNITIVE NEUROSCIENCE, 2000, 12 (01) :188-196
[43]   Aging white matter and cognition: Differential effects of regional variations in diffusion properties on memory, executive functions, and speed [J].
Kennedy, Kristen M. ;
Raz, Naftali .
NEUROPSYCHOLOGIA, 2009, 47 (03) :916-927
[44]   Aging and Emotional Memory: The Co-Occurrence of Neurophysiological and Behavioral Positivity Effects [J].
Langeslag, Sandra J. E. ;
van Strien, Jan W. .
EMOTION, 2009, 9 (03) :369-377
[45]   Aging cognition:: from neuromodulation to representation [J].
Li, SC ;
Lindenberger, U ;
Sikström, S .
TRENDS IN COGNITIVE SCIENCES, 2001, 5 (11) :479-486
[46]  
LIGHT LL, 1988, PRACTICAL ASPECTS ME, V2, P90
[47]   SENSORY FUNCTIONING AND INTELLIGENCE IN OLD-AGE - A STRONG CONNECTION [J].
LINDENBERGER, U ;
BALTES, PB .
PSYCHOLOGY AND AGING, 1994, 9 (03) :339-355
[48]   Under-recruitment and nonselective recruitment: Dissociable neural mechanisms associated with aging [J].
Logan, JM ;
Sanders, AL ;
Snyder, AZ ;
Morris, JC ;
Buckner, RL .
NEURON, 2002, 33 (05) :827-840
[49]   Preserved neural correlates of priming in old age and dementia [J].
Lustig, C ;
Buckner, RL .
NEURON, 2004, 42 (05) :865-875
[50]   Functional deactivations: Change with age and dementia of the Alzheimer type [J].
Lustig, C ;
Snyder, AZ ;
Bhakta, M ;
O'Brien, KC ;
McAvoy, M ;
Raichle, ME ;
Morris, JC ;
Buckner, RL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (24) :14504-14509