TOR signalling and control of cell growth

被引：416

作者：

Thomas, G ^{[1
]}

Hall, MN ^{[1
]}

机构：

[1] UNIV BASEL, BIOZENTRUM, DEPT BIOCHEM, CH-4056 BASEL, SWITZERLAND

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 06期

关键词：

D O I：

10.1016/S0955-0674(97)80078-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

TOR, phosphatidylinositol 3-kinase, p70(s6k), and 4E-BP1 have recently emerged as components of a major signalling pathway that is dedicated to protein translation and thus to cell growth. This pathway appears to be conserved, at least in part, in yeast, slime molds, plants, flies, and mammals. TOR and phosphatidylinositol 3-kinase control p70(s6k) and 4E-BP1, which, in turn, directly control the translation initiation machinery.

引用

页码：782 / 787

页数：6

共 49 条

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