Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling

被引:384
作者
Conti, M [1 ]
Richter, W [1 ]
Mehats, C [1 ]
Livera, G [1 ]
Park, JY [1 ]
Jin, C [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Obstet & Gynecol, Div Reprod Biol, Stanford, CA 94305 USA
关键词
D O I
10.1074/jbc.R200029200
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
65
引用
收藏
页码:5493 / 5496
页数:4
相关论文
共 65 条
[31]   Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase [J].
Lenhard, JM ;
Kassel, DB ;
Rocque, WJ ;
Hamacher, L ;
Holmes, WD ;
Patel, I ;
Hoffman, C ;
Luther, M .
BIOCHEMICAL JOURNAL, 1996, 316 :751-758
[32]   Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation - Identification and function of an inhibitory domain [J].
Lim, J ;
Pahlke, G ;
Conti, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (28) :19677-19685
[33]   Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases - A potential mechanism allowing for the coordinated regulation of PDE4D activity and targeting [J].
Liu, HG ;
Maurice, DH .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (15) :10557-10565
[34]   Dissecting the cofactor-dependent and independent bindings of PDE4 inhibitors [J].
Liu, S ;
Laliberté, F ;
Bobechko, B ;
Bartlett, A ;
Lario, P ;
Gorseth, E ;
Van Hamme, J ;
Gresser, MJ ;
Huang, Z .
BIOCHEMISTRY, 2001, 40 (34) :10179-10186
[35]   Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes [J].
MacKenzie, SJ ;
Yarwood, SJ ;
Peden, AH ;
Bolger, GB ;
Vernon, RG ;
Houslay, MD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (07) :3549-3554
[36]   Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1) [J].
MacKenzie, SJ ;
Baillie, GS ;
McPhee, I ;
MacKenzie, C ;
Seamons, R ;
McSorley, T ;
Millen, J ;
Beard, MB ;
van Heeke, G ;
Houslay, MD .
BRITISH JOURNAL OF PHARMACOLOGY, 2002, 136 (03) :421-433
[37]   PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts [J].
Marx, SO ;
Reiken, S ;
Hisamatsu, Y ;
Jayaraman, T ;
Burkhoff, D ;
Rosemblit, N ;
Marks, AR .
CELL, 2000, 101 (04) :365-376
[38]   Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B - Consequences for rolipram inhibition [J].
McPhee, I ;
Yarwood, SJ ;
Scotland, G ;
Huston, E ;
Beard, MB ;
Ross, AH ;
Houslay, ES ;
Houslay, MD .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (17) :11796-11810
[39]   Selective activation of rolipram-sensitive, cAMP-specific phosphodiesterase isoforms by phosphatidic acid [J].
Nemoz, G ;
Sette, C ;
Conti, M .
MOLECULAR PHARMACOLOGY, 1997, 51 (02) :242-249
[40]   Short term feedback regulation of cAMP in FRTL-5 thyroid cells - Role of PDE4D3 phosphodiesterase activation [J].
Oki, N ;
Takahashi, S ;
Hidaka, H ;
Conti, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (15) :10831-10837