Inherited iron overload disorders

被引：11

作者：

Andrews, NC

机构：

[1] Childrens Hosp, Howard Hughes Med Inst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

CURRENT OPINION IN PEDIATRICS | 2000年 / 12卷 / 06期

关键词：

D O I：

10.1097/00008480-200012000-00015

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Iron is an essential nutrient that is highly toxic in excess. Normal iron balance is maintained primarily by regulation of intestinal absorption of the metal from the diet. Iron overload generally results from a chronic increase in intestinal absorption. During the past 5 years, it has become apparent that there are at least eight inherited disorders of iron metabolism characterized by the toxic accumulation of iron. This review provides an update for pediatricians on the clinical features and pathogenesis of these disorders, (C) 2000 Lippincott Williams & Wilkins, Inc.

引用

收藏

页码：596 / 602

页数：7

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