3,4,6-trisubstituted-2-pyrone synthesis via the nucleophilic addition of 2-alkyl Meldrum's acid to alkynyl ketone

被引：4

作者：

Hachiya, I ^{[1
]}

Shibuya, H ^{[1
]}

Hanai, K ^{[1
]}

Shimizu, M ^{[1
]}

机构：

[1] Mie Univ, Dept Chem Mat, Tsu, Mie 5148507, Japan

来源：

LETTERS IN ORGANIC CHEMISTRY | 2004年 / 1卷 / 04期

关键词：

2-pyrone; Meldrum's acid; alkynyl ketone; dialkynyl ketone;

D O I：

10.2174/1570178043400505

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,4,6-Trisubstituted-2-pyrone synthesis via the nucleophilic addition of 2-alkyl Meldrum's acid to alkynyl ketone has been developed. The reaction of 2-alkyl Meldrum's acid with alkynyl ketones provided 3,4,6-trisubstituted-2-pyrones in good yields. The reaction of dialkynyl ketones gave 6-alkynyl-2-pyrones.

引用

收藏

页码：349 / 352

页数：4

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