Mild N-dealkylation of tertiary, benzylic amines with acid chlorides: Application to solid-phase chemistry

被引:42
作者
Miller, MW [1 ]
Vice, SF [1 ]
McCombie, SW [1 ]
机构
[1] Schering Plough Corp, Res Inst, Dept Chem Res, Kenilworth, NJ 07033 USA
关键词
D O I
10.1016/S0040-4039(98)00584-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A mild, facile cleavage of appropriately substituted tertiary, benzylic amines with acid chlorides is described for both solution and solid phase. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3429 / 3432
页数:4
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