Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells

被引：46

作者：

Kuroda, M

Mimaki, Y

Sashida, Y

Umegaki, E

Yamazaki, M

Chiba, K

Mohri, T

Kitahara, M

Yasuda, A

Naoi, N

Xu, ZW

Li, MR

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan

[2] Hokuriku Univ, Fac Pharmaceut Sci, Ishikawa, Japan

[3] Kaneka Corp, Life Sci RD Ctr, Takasago Res Labs, Hyogo, Japan

[4] Kaneka Corp, Med Devices Div, Osaka, Japan

[5] Tianjin Inst Med & Pharmaceut Sci, Tianjin, Peoples R China

来源：

PLANTA MEDICA | 2000年 / 66卷 / 06期

关键词：

D O I：

10.1055/s-2000-8611

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The MeOH extract of Epimedium sagittatum was found to show neurite outgrowth activity on cultured PC12h cells. Bioassay-guided fractionation of the MeOH extract yielded six prenylated flavonol glycosides, ikarisoside A (1), icarisid II (2), epimedoside A (3), icariin (4), epimedin B (5), and epimedokoreanoside-I (6) as the active ingredients.

引用

页码：575 / 577

页数：3

共 13 条

[1] 7 PRENYLATED FLAVONOL GLYCOSIDES FROM 2 EPIMEDIUM SPECIES [J].