Palladium-catalyzed asymmetric allylic alkylation using chiral P,N-ligands

被引：32

作者：

Mino, T ^{[1
]}

Tanaka, Y ^{[1
]}

Sakamoto, M ^{[1
]}

Fujita, T ^{[1
]}

机构：

[1] Chiba Univ, Fac Engn, Dept Mat Technol, Chiba 2638522, Japan

来源：

HETEROCYCLES | 2000年 / 53卷 / 07期

关键词：

enantioselective reaction; methoxymethylpyrrolidine; phosphine;

D O I：

10.3987/COM-00-8920

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate (8) with a dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of new chiral P,N-ligands 5 in good yields with good enantioselectives (up to 83% ee).

引用

页码：1485 / 1488

页数：4

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