Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene

被引：23

作者：

Jeong, LS ^{[1
]}

Yoo, SJ ^{[1
]}

机构：

[1] Ewha Womans Univ, Coll Pharm, Med Chem Lab, Seoul 120750, South Korea

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(98)00122-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig reaction and Mitsunobu reaction as key steps and evaluated for antiviral activity. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：847 / 852

页数：6

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