Effect of parenteral antibiotic administration on establishment of intestinal colonization by Candida glabrata in adult mice

被引：38

作者：

Pultz, NJ

Stiefel, U

Ghannoum, M

Helfand, MS

Donskey, CJ

机构：

[1] Louis Stokes Cleveland Vet Affairs Med Ctr, Infect Dis Sect, Cleveland, OH 44106 USA

[2] Louis Stokes Cleveland Vet Affairs Med Ctr, Res Sect, Cleveland, OH 44106 USA

[3] Case Western Reserve Univ, Hosp Cleveland, Div Infect Dis, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Hosp Cleveland, Ctr Med Mycol, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 01期

关键词：

D O I：

10.1128/AAC.49.1.438-440.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We examined the effect of antibiotic treatment on establishment of intestinal colonization by Candida glabrata in adult mice. Subcutaneous ceftriaxone, piperacillin-tazobactam, clindamycin, and metronidazole promoted increased density of stool colonization, whereas cefepime, levofloxacin, and aztreonam did not. These findings suggest that antibiotics that inhibit intestinal anaerobes promote C glabrata colonization.

引用

页码：438 / 440

页数：3

共 14 条

[1] The role of the gastrointestinal tract in hematogenous candidiasis: From the laboratory to the bedside [J].