Synthesis of functionalised phenylalanines using rhodium catalysis in water

被引：26

作者：

Chapman, CJ ^{[1
]}

Frost, CG ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2003年 / 345卷 / 03期

关键词：

arylation; boronic acids; C-C coupling; conjugate addition; rhodium;

D O I：

10.1002/adsc.200390039

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The efficient synthesis of substituted phenylalanine-type amino acids using a rhodium-catalysed, conjugate addition of arylboronic acids is described. The reactions are run in water and use a low loading (0.5 mol %) of rhodium catalyst.

引用

页码：353 / 355

页数：3

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