Removal of serum beta-2 microglobulin using high-performance membranes and analysis of changes in serum BMG levels after dialysis

被引:10
作者
Yasuhiro, I
Eiichi, N
Mineo, O
Muneto, Y
Toshihiro, I
Masahiro, F
Yoshifumi, N
Masahito, M
Ryuichi, M
机构
[1] Kansai Med Univ, Kohori Hosp, Div Internal Med 2, Neyagawa, Osaka 572, Japan
[2] Nakamura Clin, Osaka, Japan
基金
美国国家卫生研究院;
关键词
beta; 2-microglobulin; hemodialysis; high-performance membrane; beta 2-microglobulin removal rate;
D O I
10.1159/000013341
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Background/Aims: The present study was undertaken to analyze the beta(2)-microglobulin (BMG)-removing efficiency of high-performance membranes (HPMs) in relation to changes in serum BMG levels after dialysis. Methods: In 10 stable dialysis patients, six different HPMs were used in a crossover method. Serum BMG levels were measured immediately before dialysis, immediately after, 4h after, and immediately before the next dialysis. On the basis of these measurements, the BMG removal rate was calculated. Results: The BMG removal rate as calculated on the basis of the BMG level immediately after dialysis was 11.29% higher than the rate calculated on the basis of the BMG level 4h after dialysis. Conclusion: The BMG removal rate can be overestimated if it is calculated on the basis of the BMG level immediately after dialysis.
引用
收藏
页码:228 / 232
页数:5
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