The endoplasmic reticulum Ca2+ store:: a view from the lumen

被引：422

作者：

Meldolesi, J ^{[1
]}

Pozzan, T

机构：

[1] Univ Milan, Dept Pharmacol, B Ceccarelli Ctr Neurobiol, Milan, Italy

[2] CNR, Ctr Mol & Cellular Pharmacol, I-20133 Milan, Italy

[3] Ist Sci San Raffaele, DIBIT, I-20132 Milan, Italy

[4] Univ Padua, CNR, Ctr Biomembranes, Dept Biomed Sci, I-35100 Padua, Italy

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 01期

关键词：

D O I：

10.1016/S0968-0004(97)01143-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The endoplasmic reticulum (ER) and its specialized subcompartments such as the sarcoplasmic reticulum, is the main dynamic Ca2+ storage compartment of the cell. Key cellular functions are regulated, either directly or indirectly, by the free Ca2+ concentration in the ER. This article discusses the properties of Ca2+ storage in the ER and considers the functions that appear to be regulated by the Ca2+ stores within the ER, both in and around the ER and at a distance from it.

引用

页码：10 / 14

页数：5

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