The rise of Clostridium difficile:: the effect of length of stay, patient age and antibiotic use

被引：18

作者：

Shek, FW ^{[1
]}

Stacey, BSF ^{[1
]}

Rendell, J ^{[1
]}

Hellier, MD ^{[1
]}

Hanson, PJV ^{[1
]}

机构：

[1] Princess Margaret Hosp, Dept Gastroenterol, Swindon SN1 4JU, Wilts, England

来源：

JOURNAL OF HOSPITAL INFECTION | 2000年 / 45卷 / 03期

关键词：

Clostridium difficile; hospital acquired infection; antibiotic associated diarrhoea;

D O I：

10.1053/jhin.2000.0770

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Hospitals in the UK have recently seen a marked increase in C. difficile fur reasons which are unclear. Reduced standards of hygiene, increasingly elderly patients, greater cephalosporin use and longer hospital stay have been suggested. We retrospectively studied all cases of C. difficile diarrhoea at Princess Margaret Hospital, Swindon, over two years. Cephalosporins, patient age and LOS appeared unrelated to the rise in C. difficile; penicillins and macrolides were related. Our policy of using amoxycillin and clarithromycin for community-acquired pneumonia coincided with this study and may explain the observed rise in C. difficile. (C) 2000 The Hospital Infection.

引用

页码：235 / 237

页数：3