Fatty acid binding proteins - The evolutionary crossroads of inflammatory and metabolic responses

被引：219

作者：

Makowski, L ^{[1
]}

Hotamisligil, GS ^{[1
]}

机构：

[1] Harvard Univ, Sch Publ Hlth, Dept Genet & Complex Dis, Boston, MA USA

来源：

JOURNAL OF NUTRITION | 2004年 / 134卷 / 09期

关键词：

fatty acid binding protein (FABP); Metabolic Syndrome; inflammation; obesity; insulin resistance;

D O I：

10.1093/jn/134.9.2464S

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Fatty acid binding proteins (FABPs) are members of a highly conserved family of proteins with the task of protecting a cell's delicate lipid balance. Yet they fail when faced with metabolic or inflammatory stress, turning the cytosol into an inhospitable environment with less than ideal outcomes. This review will focus on how FABPs direct lipid traffic and simultaneously control inflammatory and metabolic pathways under the pressures of the Metabolic Syndrome.

引用

页码：2464S / 2468S

页数：5

共 56 条

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