Functions of α3β1 integrin

被引:162
作者
Kreidberg, JA
机构
[1] Childrens Hosp, Dept Med, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA
关键词
D O I
10.1016/S0955-0674(00)00130-7
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
alpha 3 beta 1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha 3 beta 1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.
引用
收藏
页码:548 / 553
页数:6
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