Recognition and treatment of psoriasis - Special considerations in elderly patients

被引:14
作者
Bonifati, C
Carducci, M
Mussi, A
D'Auria, L
Ameglio, F
机构
[1] Inst S Gallicano, Dept Dermatol, Rome, Italy
[2] Inst S Gallicano, Clin Pathol Lab, Rome, Italy
关键词
D O I
10.2165/00002512-199812030-00002
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Psoriasis is a chronic dermatological disorder that affects 1 to 2% of the general population. Although its aetiology is still unknown, the importance of genetic factors has been confirmed by many studies, mainly in young individuals. With respect to clinical features, plaque-type psoriasis (localised or generalised) is the most common form. At present, there is no cure for psoriasis and the available treatments can only temporarily clear the skin manifestations. The choice of treatment regimen for psoriasis is based on the severity of the disease, the patient's gender, age, treatment history and level of compliance, and the physician's personal experience. All therapies for psoriasis have different and potentially toxic effects. Therefore, a good knowledge of their relative and absolute contraindications, adverse effects and interactions with other drugs is mandatory. The elderly represent a significant proportion of patients with psoriasis because its prevalence increases with age. Physicians, particularly general practitioners, dermatologists and gerontologists, must be aware of the problems that the treatment of psoriasis in the elderly can present. This is especially important because of the increased risk of adverse drug reactions in the elderly.
引用
收藏
页码:177 / 190
页数:14
相关论文
共 101 条
[71]  
NORRIS PG, 1994, BRIT J DERMATOL, V130, P246
[72]  
ONIGSMANN H, 1987, DERMATOLOGY GEN MED, P1533
[73]   THE RETINOIDS - A REVIEW OF THEIR CLINICAL-PHARMACOLOGY AND THERAPEUTIC USE [J].
ORFANOS, CE ;
EHLERT, R ;
GOLLNICK, H .
DRUGS, 1987, 34 (04) :459-503
[74]  
ORTONNE JP, 1994, NOUV DERMATOL, V13, P746
[75]  
PEPEU G, 1990, DERMATOLOGIA OGGI, V4, P58
[76]   GOECKERMAN TREATMENT OF PSORIASIS [J].
PERRY, HO ;
SODERSTR.CW ;
SCHULZE, RW .
ARCHIVES OF DERMATOLOGY, 1968, 98 (02) :178-&
[77]  
PIPPIONE M, 1990, DERMATOLOGY OGGI, V4, P27
[78]   SKIN-CANCER IN PATIENTS WITH PSORIASIS TREATED WITH COAL-TAR - A 25-YEAR FOLLOW-UP-STUDY [J].
PITTELKOW, MR ;
PERRY, HO ;
MULLER, SA ;
MAUGHAN, WZ ;
OBRIEN, PC .
ARCHIVES OF DERMATOLOGY, 1981, 117 (08) :465-468
[79]   PUSTULAR AND ERYTHRODERMIC PSORIASIS [J].
PRYSTOWSKY, JH ;
COHEN, PR .
DERMATOLOGIC CLINICS, 1995, 13 (04) :757-&
[80]   LONG-TERM USE OF TOPICAL CALCIPOTRIOL IN CHRONIC PLAQUE PSORIASIS [J].
RAMSAY, CA ;
BERTHJONES, J ;
BRUNDIN, G ;
CUNLIFFE, WJ ;
DUBERTRET, L ;
VANDEKERKHOF, PCM ;
MENNE, T ;
WEGMANN, E .
DERMATOLOGY, 1994, 189 (03) :260-264