Oral Helicobacter pylori:: Can we stomach it?

被引：87

作者：

Dowsett, SA ^{[1
]}

Kowolik, MJ ^{[1
]}

机构：

[1] Indiana Univ, Sch Dent, Dept Periodont & Allied Dent Programs, Indianapolis, IN 46202 USA

来源：

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE | 2003年 / 14卷 / 03期

关键词：

Helicobacter pylori; transmission; oral; mouth; dental plaque; POLYMERASE-CHAIN-REACTION; GASTRIC BIOPSY SAMPLES; DENTAL PLAQUE; HIGH PREVALENCE; PCR ASSAY; CAMPYLOBACTER-PYLORI; PERMANENT RESERVOIR; DYSPEPTIC PATIENTS; DNA FINGERPRINTS; INFECTION;

D O I：

10.1177/154411130301400307

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Helicobacter pylori infection is one of the most common in man. The bacterium primarily resides in the human stomach, where it plays a significant role in gastric disease. If the spread of H. pylori is to be prevented, an understanding of the transmission process is essential. The oral cavity has been proposed as a reservoir for gastric H. pylori, which has been detected by culture and PCR in both dental plaque and saliva. This review will discuss the evidence for the role of the oral cavity in the transmission of gastric H. pylori. Moreover, the difficulties encountered in addressing this topic, possible directions for future research, and the implications for the dental profession are discussed.

引用

页码：226 / 233

页数：8