Needle-type glucose microbiosensor based on glucose oxidase immobilised in an overoxidised polypyrrole film (an in-vitro study)

被引：18

作者：

Quinto, M

Losito, I

Palmisano, F

Zambonin, CG

机构：

[1] Univ Bari, Dipartmento Chim, I-70126 Bari, Italy

[2] Univ Basilicata, Dipartimento Chim, I-85100 Potenza, Italy

来源：

FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 2000年 / 367卷 / 08期

关键词：

D O I：

10.1007/s002160000489

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A fast response, needle-type glucose micro-biosensor has been fabricated by a one-step electrochemical immobilisation of glucose oxidase in a polypyrrole film. The sensor shows a remarkable rejection of electroactive interferences, especially paracetamol. The maximum bias observed in the worst situation never exceeded the value of 6%. The fabrication procedure delivered very reproducible devices and the sensitivity of a newly prepared biosensor was typically 650 nAmM(-1)cm(-2). The kinetic parameters, obtained from an existing model, permitted to understand the sensor behaviour.

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页码：692 / 696

页数：5

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