Spasmolytic constituents from Eucalyptus camaldulensis var. obtusa leaves

被引：26

作者：

Begum, S ^{[1
]}

Farhat

Sultana, I

Siddiqui, BS

Shaheen, F

Gilani, AH

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Karachi 75270, Pakistan

[2] Aga Khan Univ, Coll Med, Dept Physiol & Pharmacol, Karachi 74800, Pakistan

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 09期

关键词：

D O I：

10.1021/np9902340

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical studies on the leaves of Eucalyptus camaldulensis var. obtusa have resulted in the isolation of a new triterpenoid camaldulin (3 beta-formyloxyurs-11-en-28,13 beta-olide) (1) along with ursolic acid lactone acetate (2), ursolic acid lactone (3), betulinic acid (4), and beta-sitosterol 3-O-beta-D-glucopyranoside (5). The structures were assigned on the basis of 1D and 2D NMR studies. Compounds 1-3 were tested for spasmolytic activity and were found to possess calcium antagonist activity.

引用

页码：1265 / 1268

页数：4