Protein subcellular relocalization: a new perspective on the origin of novel genes

被引：46

作者：

Byun-McKay, S. Ashley ^{[1
]}

Geeta, R.

机构：

[1] Fairfield Univ, Dept Biol, Fairfield, CT 06824 USA

[2] SUNY Stony Brook, Dept Ecol & Evolut, Stony Brook, NY 11794 USA

来源：

TRENDS IN ECOLOGY & EVOLUTION | 2007年 / 22卷 / 07期

关键词：

D O I：

10.1016/j.tree.2007.05.002

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

Gene duplication is considered to be the most important evolutionary process for generating novel genes. However, the mechanisms involved in the evolution of such genetic innovations remain unclear. There is compelling evidence to suggest that changing the subcellular location of a protein can also alter its function, and that diversity in subcellular targeting within gene families is common. Here, we introduce the idea that protein subcellular relocalization might be an important evolutionary mechanism for the origins of new genes.

引用

页码：338 / 344

页数：7

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