Leukemogenesis: Small differences in Myb have large effects

被引：9

作者：

Graf, T ^{[1
]}

机构：

[1] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 10期

关键词：

D O I：

10.1016/S0960-9822(98)70220-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The avian retroviruses E26 and AMV carry mutated versions of the gene encoding the cellular transcription factor c-Myb. Surprisingly, these two mutant forms of Myb differ in the subsets of myeloid cells that they transform, the target genes that they activate, and the way in which they are regulated. (C) Current Biology Ltd ISSN 0960-9822.

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收藏

页码：R353 / R355

页数：3

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