Searching genomes for ribozymes and riboswitches

被引：42

作者：

Hammann, Christian

Westhof, Eric

机构：

[1] Univ Strasbourg, Inst Biol Mol & Cellulaire, CNRS, Architecture & Reactivite ARN, F-67084 Strasbourg, France

[2] Univ Kassel, Dept Genet, Res Grp Mol Interact, D-34132 Kassel, Germany

来源：

GENOME BIOLOGY | 2007年 / 8卷 / 04期

关键词：

D O I：

10.1186/gb-2007-8-4-210

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes.

引用

页数：11

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