Fabrication of celtular multilayers with nanometer-sized extracellular matrix films

被引：161

作者：

Matsusaki, Michiya

Kadowaki, Koji

Nakahara, Yoshio

Akashi, Mitsuru

机构：

[1] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Suita, Osaka 565, Japan

[2] Wakayama Univ, Fac Syst Engn, Dept Appl Chem, Wakayama 640, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 25期

关键词：

cell adhesion; layered compounds; multilayers; proteins; thin films;

D O I：

10.1002/anie.200701089

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Layer it on: Cellular multilayers were fabricated by preparing nanometer-sized extracellular matrix (ECM) films (6-nm thick) with fibronectin (FN) and gelatin on the surface of each cell layer. The four-layer cellular architecture was well organized and self-standing. Xenogenic human bilayer architectures similar to blood vessels were prepared by fabrication of the nanofilms on cell surfaces. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：4689 / 4692

页数：4

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