Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008

被引：77

作者：

Yu, Haiyang ^{[1
,2
]}

Chen, Wei ^{[1
,2
]}

Chang, Hongwei ^{[2
,3
]}

Tang, Renshu ^{[1
,2
]}

Zhao, Jun ^{[1
,2
]}

Gan, Lin ^{[1
,2
]}

Liu, Boyu ^{[1
,2
]}

Chen, Jason ^{[2
,4
]}

Wang, Mingli ^{[1
,2
]}

机构：

[1] Minist Educ China & Anhui Prov, Key Lab Gene Resource Utilizat Severe Dis, Hefei 230032, Anhui, Peoples R China

[2] Anhui Med Univ, Dept Microbiol, Hefei 230032, Anhui, Peoples R China

[3] Luan Ctr Dis Control & Prevent, Luan 237000, Anhui, Peoples R China

[4] Columbia Univ, Dept Pathol & Cell Biol, New York, NY 10032 USA

来源：

VIRUS GENES | 2010年 / 41卷 / 01期

关键词：

Hand; foot; and mouth disease; Enterovirus; 71; VP1; gene; Genotype A; Phylogenetic analysis; MOUTH-DISEASE; MOLECULAR EPIDEMIOLOGY; OUTBREAK; FOOT; HAND; SEQUENCE; STRAINS; INFECTION; EVOLUTION; CHILDREN;

D O I：

10.1007/s11262-010-0472-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Enterovirus 71 (EV71) strains from children were characterized by full-length VP1 nucleotide sequencing. Out of 22 clinical specimens, five isolates identified as EV71 were recovered by virus isolation. The VP1 sequences of the five isolates had more than 97.4% sequence identity with prototype virus BrCr, clustering in the genotype A lineage. This represents the first record of genotype A EV71 in China since the BrCr prototype strain was discovered in the USA in 1969.

引用

页码：1 / 4

页数：4

共 24 条

[1] Identification of enterovirus 71 isolates from an outbreak of hand, foot and mouth disease (HFMD) with fatal cases of encephalomyelitis in Malaysia [J].

AbuBakar, S ;

Chee, HY ;

Al-Kobaisi, MF ;

Jiang, XS ;

Chua, KB ;

Lam, SK .

VIRUS RESEARCH, 1999, 61 (01) :1-9

[2] Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys [J].

Arita, M ;

Shimizu, H ;

Nagata, N ;

Ami, Y ;

Suzaki, Y ;

Sata, T ;

Iwasaki, T ;

Miyamura, T .

JOURNAL OF GENERAL VIROLOGY, 2005, 86 :1391-1401

[3] Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998 [J].

Brown, BA ;

Oberste, MS ;

Alexander, JP ;

Kennett, ML ;

Pallansch, MA .

JOURNAL OF VIROLOGY, 1999, 73 (12) :9969-9975

[4]

Burland T G, 2000, Methods Mol Biol, V132, P71

[5]

Cardosa MJ, 2003, EMERG INFECT DIS, V9, P461

[6] Deaths of children during an outbreak of hand, foot, and mouth disease in Sarawak, Malaysia: Clinical and pathological characteristics of the disease [J].

Chan, LG ;

Parashar, UD ;

Lye, MS ;

Ong, FGL ;

Zaki, SR ;

Alexander, JP ;

Ho, KK ;

Han, LL ;

Pallansch, MA ;

Suleiman, AB ;

Jegathesan, M ;

Anderson, LJ .

CLINICAL INFECTIOUS DISEASES, 2000, 31 (03) :678-683

[7] Outbreak of central nervous system disease associated with hand, foot, and mouth disease in Japan during the summer of 2000: Detection and molecular epidemiology of enterovirus 71 [J].

Fujimoto, T ;

Chikahira, M ;

Yoshida, S ;

Ebira, H ;

Hasegawa, A ;

Totsuka, A ;

Nishio, O .

MICROBIOLOGY AND IMMUNOLOGY, 2002, 46 (09) :621-627

[8] OUTBREAK OF POLIOMYELITIS-LIKE PARALYSIS ASSOCIATED WITH ENTEROVIRUS-71 [J].

HAYWARD, JC ;

GILLESPIE, SM ;

KAPLAN, KM ;

PACKER, R ;

PALLANSCH, M ;

PLOTKIN, S ;

SCHONBERGER, LB .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1989, 8 (09) :611-616

[9]

Howley, 2007, FIELDS VIROLOGY, V5, P795

[10] The circulation of subgenogroups B5 and C5 of enterovirus 71 in Taiwan from 2006 to 2007 [J].

Huang, Yuan-Pin ;

Lin, Tsuey-Li ;

Kuo, Chuan-Yi ;

Lin, Miao-Wen ;

Yao, Ching-Yuan ;

Liao, Hui-Wen ;

Hsu, Li-Ching ;

Yang, Chen-Fu ;

Yang, Jyh-Yuan ;

Chen, Pei-Jer ;

Wu, Ho-Sheng .

VIRUS RESEARCH, 2008, 137 (02) :206-212

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