The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3)

被引：6

作者：

Berry, GT

Mallee, JJ

Blouin, JL

Antonarakis, SE

机构：

[1] UNIV GENEVA,SCH MED,DEPT GENET,GENEVA,SWITZERLAND

[2] UNIV GENEVA,SCH MED,DEPT MICROBIOL,GENEVA,SWITZERLAND

[3] CANTONAL HOSP,DIV MED GENET,GENEVA,SWITZERLAND

来源：

CYTOGENETICS AND CELL GENETICS | 1996年 / 73卷 / 1-2期

关键词：

D O I：

10.1159/000134311

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3) was recently cloned and localized to the region of 21q22. Fine mapping of this gene was accomplished by identifying YAC clones that contain SLC5A3 and utilizing known STS markers for 21q22.1 and 21q22.2 subbands that map to the positive YAC clones. Two bacteriophage P1 clones containing the SLC5A3 gene gave a positive PCR product when screened with the 21q22.1 marker VNO2, an expressed sequence tag (EST00541). Through DNA sequence analysis, it was determined that this STS marker is part of the 3' untranslated region of the SLC5A3 gene.

引用

页码：77 / 78

页数：2

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