Ventilator-associated pneumonia: A review

被引：230

作者：

Joseph, Noyal Mariya ^{[1
]}

Sistla, Sujatha ^{[1
]}

Dutta, Tarun Kumar ^{[2
]}

Badhe, Ashok Shankar ^{[3
]}

Parija, Subhash Chandra ^{[1
]}

机构：

[1] JIPMER, Dept Microbiol, Pondicherry 605006, India

[2] JIPMER, Dept Med, Pondicherry 605006, India

[3] JIPMER, Dept Anaesthesiol & Crit Care, Pondicherry 605006, India

来源：

EUROPEAN JOURNAL OF INTERNAL MEDICINE | 2010年 / 21卷 / 05期

关键词：

Ventilator-associated pneumonia; Risk factors; Multi-drug resistant pathogens; Diagnosis; Biomarkers; Treatment; SPECIMEN BRUSH SAMPLES; INTENSIVE-CARE UNITS; C-REACTIVE PROTEIN; RISK-FACTORS; CRITICALLY-ILL; MECHANICAL VENTILATION; NOSOCOMIAL INFECTIONS; RESPIRATORY-TRACT; BETA-LACTAMASES; QUALITATIVE CULTURES;

D O I：

10.1016/j.ejim.2010.07.006

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Ventilator-associated pneumonia (VAP) is the most frequent intensive-care-unit (ICU)-acquired infection, with an incidence ranging from 6 to 52% [1,2,3,4]. Several studies have shown that critically ill patients are at high risk for getting such nosocomial infections [3,4]. VAP continues to be a major cause of morbidity, mortality and increased financial burden in ICUs [5,6,7,8]. Over the years there has been a significant advance in our understanding of ventilator associated pneumonia. This article reviews the various aspects of VAP such as definition, risk factors, etiological agents, diagnosis, treatment and prevention with emphasis on the recent advances. (C) 2010 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

引用

页码：360 / 368

页数：9

共 89 条

[1]

Bronchoscopy in ventilator-associated pneumonia - Agreement of calibrated loop and serial dilution [J].

Afessa, Bekele ;

Hubmayr, Rolf D. ;

Vetter, Emily A. ;

Keegan, Mark T. ;

Swanson, Karen L. ;

Baddour, Larry M. ;

Cockerill, Franklin R., III ;

Peters, Steve G. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 173 (11) :1229-1232

[2]

Ventilator associated pneumonia and infection control [J].

Alp E. ;

Voss A. .

Annals of Clinical Microbiology and Antimicrobials, 5 (1)

[3]

Nosocomial infections in a medical-surgical intensive care unit [J].

Aly, Nasser Yehia A. ;

Al-Mousa, Haifaa H. ;

Al Asar, El Sayed M. .

MEDICAL PRINCIPLES AND PRACTICE, 2008, 17 (05) :373-377

[4]

DIAGNOSIS OF NOSOCOMIAL BACTERIAL PNEUMONIA IN ACUTE, DIFFUSE LUNG INJURY [J].

ANDREWS, CP ;

COALSON, JJ ;

SMITH, JD ;

JOHANSON, WG .

CHEST, 1981, 80 (03) :254-258

[5]

Guidelines for the management, of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia [J].

不详 .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 171 (04) :388-416

[6]

Apostolopoulou Eleni, 2003, Respir Care, V48, P681

[7]

THE STANDARDIZATION OF CRITERIA FOR PROCESSING AND INTERPRETING LABORATORY SPECIMENS IN PATIENTS WITH SUSPECTED VENTILATOR-ASSOCIATED PNEUMONIA [J].

BASELSKI, VS ;

ELTORKY, M ;

COALSON, JJ ;

GRIFFIN, JP .

CHEST, 1992, 102 (05) :S571-S579

[8]

Cross-colonisation with Pseudomonas aeruginosa of patients in an intensive care unit [J].

Bergmans, DCJJ ;

Bonten, MJM ;

van Tiel, FH ;

Gaillard, CA ;

van der Geest, S ;

Wilting, RM ;

de Leeuw, PW ;

Stobberingh, EE .

THORAX, 1998, 53 (12) :1053-1058

[9]

Reproducibility of quantitative cultures of endotracheal aspirates from mechanically ventilated patients [J].

Bergmans, DCJJ ;

Bonten, MJM ;

DeLeeuw, PW ;

Stobberingh, EE .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (03) :796-798

[10]

Value of gram stain examination of lower respiratory tract secretions for early diagnosis of nosocomial pneumonia [J].

Blot, F ;

Raynard, B ;

Chachaty, E ;

Tancrède, C ;

Antoun, S ;

Nitenberg, G .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 162 (05) :1731-1737

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