A practical Buchwald-Hartwig amination of 2-bromopyridines with volatile amines

被引：25

作者：

Li, Jie Jack ^{[1
]}

Wang, Zhi ^{[1
]}

Mitchell, Lorna H. ^{[1
]}

机构：

[1] Pfizer Global Res & Dev, Michigan Labs, Dept Chem, Ann Arbor, MI 48106 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 09期

关键词：

D O I：

10.1021/jo070366v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical Buchwald-Hartwig amination of 2-bromopyridines with volatile amines is developed in sealed tubes. The method provides an expedient entry to a variety of secondary and tertiary aminopyridines that are otherwise not readily synthesized.

引用

页码：3606 / 3607

页数：2

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