Mammalian phylogenomics comes of age

被引:259
作者
Murphy, WJ
Pevzner, PA
O'Brien, SJ
机构
[1] NCI, Lab Genom Divers, SAIC Frederick, Basic Res Lab, Frederick, MD 21702 USA
[2] Univ Calif San Diego, Dept Comp Sci & Engn, La Jolla, CA USA
[3] NCI, Lab Genom Divers, Frederick, MD 21702 USA
关键词
D O I
10.1016/j.tig.2004.09.005
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The relatively new field of phylogenomics is beginning to reveal the potential of genomic data for evolutionary studies. As the cost of whole genome sequencing falls, anticipation of complete genome sequences from divergent species, reflecting the major lineages of modern mammals, is no longer a distant dream. In this article, we describe how comparative genomic data from mammals is progressing to resolve long-standing phylogenetic controversies, to refine dogma on how chromosomes evolve and to guide annotation of human and other vertebrate genomes.
引用
收藏
页码:631 / 639
页数:9
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