Wall coating for capillary electrophoresis on microchips

被引：121

作者：

Dolník, V ^{[1
]}

机构：

[1] Alcor BioSeparat, Mountain View, CA 94043 USA

来源：

ELECTROPHORESIS | 2004年 / 25卷 / 21-22期

关键词：

capillary electrophoresis; microchip; miniaturization; review; surface modification; wall coating;

D O I：

10.1002/elps.200406113

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review article with 116 references describes recent developments in the preparation of wall coatings for capillary electrophoresis (CE) on a microchip. It deals with both dynamic and permanent coatings and concentrates on the most frequently used microchip materials including glass, poly(methyl methacrylate), poly(dimethyl siloxane), polycarbonate, and poly(ethylene terephthalate glycol). Characterization of the channel surface by measuring electroosmotic mobility and water contact angle of the surface is included as well. The utility of the microchips with coated channels is demonstrated by examples of CE separations on these chips.

引用

页码：3589 / 3601

页数：13

共 124 条

[1] Poly-N-hydroxyethylacrylamide as a novel, adsorbed coating for protein separation by capillary electrophoresis [J].