Nickel-catalyzed 1,4-addition of trialkylboranes to α,β-unsaturated esters:: Dramatic enhancement by addition of methanol

被引：35

作者：

Hirano, Koji ^{[1
]}

Yorimitsu, Hideki ^{[1
]}

Oshima, Koichiro ^{[1
]}

机构：

[1] Kyoto Univ, Dept Chem Mat, Grad Sch Engn, Nishikyo Ku, Kyoto 6158510, Japan

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 08期

关键词：

D O I：

10.1021/ol070288y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Nickel catalyst systems for 1,4-addition of trialkylboranes to alpha,beta-unsaturated esters have been developed. Addition of methanol was found to be essential for the alkylation reaction with 9-alkyl-9-BBNs.

引用

页码：1541 / 1544

页数：4

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