Cyclometalation Using d-Block Transition Metals: Fundamental Aspects and Recent Trends

A study was conducted some of the fundamental aspects and the latest trends in the field of cyclometalation using d-block transition metals. It was revealed that cyclometalation had emerged as one of the most popular organometallic reactions, providing a simple entry to organometallic compounds. It allowed for the investigation of the essential aspects governing the metal-mediated activation of unreactive bonds, such as the C-H bond. The study covered seminal fundamental literature and the latest highlights and the trends that emerged till early 2009. Cyclometalation gained significance due to the reaction representing the mildest route for achieving strong C-H and C-R bonds. It had also emerged as an attractive and versatile synthetic method for creating organometallic entities with significantly wide application potential.