High frequency repetitive transcranial magnetic over the medial cerebellum induces a shift in the prefrontal electroencephalography gamma spectrum: a pilot study in humans

被引：78

作者：

Schutter, DJLG

van Honk, J

d'Alfonso, AAL

Peper, JS

Panksepp, J

机构：

[1] Univ Utrecht, Affect Neurosci Sect, Helmholtz Res Inst, NL-3584 CS Utrecht, Netherlands

[2] Albert Schweitzer Hosp, Dept Internal Med, Dordrecht, Netherlands

[3] Bowling Green State Univ, Dept Psychol, Bowling Green, OH 43403 USA

来源：

NEUROSCIENCE LETTERS | 2003年 / 336卷 / 02期

关键词：

cerebellum; fast repetitive transcranial magnetic; prefrontal cortex; electroencephalography; lateralization;

D O I：

10.1016/S0304-3940(02)01077-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the present study the anatomical projections from the medial cerebellum to the prefrontal cortex (PFC) were investigated in healthy human subjects, using high frequency repetitive transcranial magnetic (rTMS) stimulation and electro-encephalography (EEG). Medial cerebellar rTMS, compared to placebo induced a significant shift in anterior asymmetry, from left to right dominance in the fast(30-50 Hz) EEG spectrum, whereas occipital and lateral cerebellum stimulation did not show such an effect. Moreover elevations in mood and alertness were reported again after medial cerebellar stimulation only. Taken together, these data confirm and further specify the assumed cerebellar modulation of PFC activity and affect. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：73 / 76

页数：4

共 21 条

[1] Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion [J].