What determines glomerular capillary permeability?

被引：113

作者：

Deen, WM

机构：

[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

[2] MIT, Div Biol Engn, Cambridge, MA 02139 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2004年 / 114卷 / 10期

关键词：

D O I：

10.1172/JCI200423577

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

There have been exciting recent advances in our understanding of the structural and molecular biology of the glomerular slit diaphragm, as described in a report in this issue of the JCI (see the related article beginning on page 1475). These findings, combined with data on the permeability of the basement membrane and evidence that the endothelium may be a more important barrier than often supposed, are allowing a clearer understanding to emerge of how the 3 parts of the glomerular capillary wall jointly determine its functional properties.

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页码：1412 / 1414

页数：3

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