Comparison of the planar and coaxial field asymmetrical waveform ion mobility spectrometer (FAIMS)

被引：53

作者：

Krylov, EV ^{[1
]}

机构：

[1] New Mexico State Univ, Dept Chem & Biochem, Dept 3C, Las Cruces, NM 88003 USA

来源：

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY | 2003年 / 225卷 / 01期

关键词：

FAIMS; ion mobility; mobility dependence; diffusion losses; focusing;

D O I：

10.1016/S1387-3806(02)01037-0

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

A method and apparatus for ion separation in gases using the dependence of ion mobility coefficient on electric field strength are briefly described (including effect of ion focusing in apparatus with coaxial design of separation chamber). A mathematical model described ions transition for both coaxial and planar separation chamber design is proposed. The model has been verified by our own and published experimental data. Using the proposed model comparative analysis of the planar and coaxial apparatus is conducted by comparison of ion diffusion losses (sensitivity) and response time (speed of operation). Qualitative and quantitative advantages and disadvantages of both variants are considered. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：39 / 51

页数：13

共 17 条

[1] A NEW METHOD OF SEPARATION OF MULTI-ATOMIC IONS BY MOBILITY AT ATMOSPHERIC-PRESSURE USING A HIGH-FREQUENCY AMPLITUDE-ASYMMETRIC STRONG ELECTRIC-FIELD [J].

BURYAKOV, IA ;

KRYLOV, EV ;

NAZAROV, EG ;

RASULEV, UK .

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1993, 128 (03) :143-148

[2]

BURYAKOV IA, 1989, Patent No. 1485808

[3]

BURYAKOV IA, 2000, P 9 INT C ION MOB SP

[4]

BURYAKOV IA, 1988, Patent No. 1412447

[5]

CARNAHAN B, 1995, P 4 INT WORKSH ION M

[6]

Eiceman GA, 2001, INT J ION MOBILITY S, V3, P15

[7]

Gorshkov MP, 1982, Inventor's certificate of USSR No. 966583, G01N27/62, Patent No. 966583

[8] Atmospheric pressure ion focusing in a high-field asymmetric waveform ion mobility spectrometer [J].

Guevremont, R ;

Purves, RW .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1999, 70 (02) :1370-1383

[9] Calculation of ion mobilities from electrospray ionization high-field asymmetric waveform ion mobility spectrometry mass spectrometry [J].

Guevremont, R ;

Barnett, DA ;

Purves, RW ;

Viehland, LA .

JOURNAL OF CHEMICAL PHYSICS, 2001, 114 (23) :10270-10277

[10] Use of ion mobility spectrometry to determine low levels of impurities in gases [J].

Ketkar, SN ;

Dheandhanoo, S .

ANALYTICAL CHEMISTRY, 2001, 73 (11) :2554-2557

← 1 2 →