BioNet: an R-Package for the functional analysis of biological networks

被引：175

作者：

Beisser, Daniela ^{[1
]}

Klau, Gunnar W. ^{[2
]}

Dandekar, Thomas ^{[1
]}

Muller, Tobias ^{[1
]}

Dittrich, Marcus T. ^{[1
]}

机构：

[1] Univ Wurzburg, Dept Bioinformat, Bioctr, D-97074 Wurzburg, Germany

[2] CWI, Life Sci Grp, NL-1098 XG Amsterdam, Netherlands

来源：

BIOINFORMATICS | 2010年 / 26卷 / 08期

关键词：

D O I：

10.1093/bioinformatics/btq089

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

Motivation: Increasing quantity and quality of data in transcriptomics and interactomics create the need for integrative approaches to network analysis. Here, we present a comprehensive R-package for the analysis of biological networks including an exact and a heuristic approach to identify functional modules. Results: The BioNet package provides an extensive framework for integrated network analysis in R. This includes the statistics for the integration of transcriptomic and functional data with biological networks, the scoring of nodes as well as methods for network search and visualization.

引用

页码：1129 / 1130

页数：2

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