Emergence of restless legs syndrome during subthalamic stimulation for Parkinson disease

被引：89

作者：

Kedia, S

Moro, E

Tagliati, M

Lang, AE

Kumar, R

机构：

[1] Univ Colorado, Hlth Sci Ctr, Denver, CO USA

[2] Colorado Neurol Inst, Englewood, CO USA

[3] Beth Israel Deaconess Med Ctr, New York, NY 10003 USA

[4] Univ Hlth Network, Movement Disorders Ctr, Toronto, ON, Canada

来源：

NEUROLOGY | 2004年 / 63卷 / 12期

关键词：

D O I：

10.1212/01.WNL.0000147288.26029.B8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors systematically studied the emergence of restless legs syndrome (RLS) after subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson disease (PD). Postoperatively, 11 of 195 patients with STN DBS reported new problematic symptoms of RLS. The mean reduction in antiparkinsonian medication was 74%. The mean RLS score at diagnosis was 15 (+/-5.9) of a possible 24 points and after symptomatic drug therapy 4.3 (+/-3.1) points. Reduction of antiparkinsonian medication during STN DBS may unmask symptoms of RLS and complicate therapy of both RLS and PD.

引用

页码：2410 / 2412

页数：3

共 12 条

[1] Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome [J].

Connor, JR ;

Boyer, PJ ;

Menzies, SL ;

Dellinger, B ;

Allen, RP ;

Ondo, WG ;

Earley, CJ .

NEUROLOGY, 2003, 61 (03) :304-309

[2]

Montplaisir J, 1994, PRINCIPLES PRACTICE, P589

[3]

Ondo W, 1999, MOVEMENT DISORD, V14, P138, DOI 10.1002/1531-8257(199901)14:1<138::AID-MDS1023>3.3.CO

[4]

2-1

[5] Exploring the relationship between Parkinson disease and restless legs syndrome [J].

Ondo, WG ;

Vuong, KD ;

Jankovic, J .

ARCHIVES OF NEUROLOGY, 2002, 59 (03) :421-424

[6]

Rye DB, 1999, ANN NEUROL, V46, P800, DOI 10.1002/1531-8249(199911)46:5<800::AID-ANA22>3.0.CO

[7]

2-F

[8] Subthalamic deep brain stimulation does not induce striatal dopamine release in Parkinson's disease [J].

Strafella, AP ;

Sadikot, AF ;

Dagher, A .

NEUROREPORT, 2003, 14 (09) :1287-1289

[9] Striatal dopaminergic function in restless legs syndrome -: 18F-dopa and 11C-raclopride PET studies [J].

Turjanski, N ;

Lee, AJ ;

Brooks, DJ .

NEUROLOGY, 1999, 52 (05) :932-937

[10] Safety and efficacy of pallidal or subthalamic nucleus stimulation in advanced PD [J].

Volkmann, J ;

Allert, N ;

Voges, J ;

Weiss, PH ;

Freund, HJ ;

Sturm, V .

NEUROLOGY, 2001, 56 (04) :548-551

← 1 2 →