(Z)-3-(2-{2-[1-(4-Hydroxyphenyl)ethylidene]hydrazin-1-yl}-1,3-thiazol-4-yl)-2H-chromen-2-one

被引:4
作者
Arshad, Afsheen [2 ]
Osman, Hasnah [2 ]
Lam, Chan Kit [3 ]
Quah, Ching Kheng [1 ]
Fun, Hoong-Kun [1 ]
机构
[1] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town 11800, Malaysia
[2] Univ Sains Malaysia, Sch Chem Sci, George Town 11800, Malaysia
[3] Univ Sains Malaysia, Sch Pharmaceut Sci, George Town 11800, Malaysia
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷
关键词
X-RAY; DERIVATIVES; INHIBITORS; DIFFRACTION; CELLS;
D O I
10.1107/S1600536810021604
中图分类号
O7 [晶体学];
学科分类号
070301 [无机化学];
摘要
In the title compound, C(20)H(15)N(3)O(3)S, an intramolecular C-H center dot center dot center dot O hydrogen bond generates an S(6) ring motif. The chromene ring system is inclined at dihedral angles of 14.21 (9) and 9.91 (10)degrees, respectively, with respect to the thiazole and benzene rings. The thiazole ring makes a dihedral angle of 24.06 (11)degrees with the benzene ring. In the crystal structure, O-H center dot center dot center dot O hydrogen bonds link the molecules into a zigzag chain along [20 (1) over bar]. Weak N-H center dot center dot center dot O and C-H center dot center dot center dot O interactions connect the chains into a three-dimensional network. pi-pi stacking interactions with a centroid-centroid distance of 3.4209 (14) angstrom are also observed between the chains.
引用
收藏
页码:O1632 / U1106
页数:12
相关论文
共 16 条
[1]
TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS [J].
ALLEN, FH ;
KENNARD, O ;
WATSON, DG ;
BRAMMER, L ;
ORPEN, AG ;
TAYLOR, R .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (12) :S1-S19
[2]
No effect of the novel antidiabetic agent nateglinide on the pharmacokinetics and anticoagulant properties of warfarin in healthy volunteers [J].
Anderson, DM ;
Shelley, S ;
Crick, N ;
Buraglio, M .
JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 42 (12) :1358-1365
[3]
[Anonymous], 2009, APEX2 SAINT SADABS
[4]
3-{2-[2-(2-Fluorobenzylidene)hydrazinyl]-1,3-thiazol-4-yl}-2H-chromen-2-one [J].
Arshad, Afsheen ;
Osman, Hasnah ;
Lam, Chan Kit ;
Quah, Ching Kheng ;
Fun, Hoong-Kun .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O1446-U1734
[5]
PATTERNS IN HYDROGEN BONDING - FUNCTIONALITY AND GRAPH SET ANALYSIS IN CRYSTALS [J].
BERNSTEIN, J ;
DAVIS, RE ;
SHIMONI, L ;
CHANG, NL .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1995, 34 (15) :1555-1573
[6]
A NITROGEN-GAS-STREAM CRYOSTAT FOR GENERAL X-RAY-DIFFRACTION STUDIES [J].
COSIER, J ;
GLAZER, AM .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1986, 19 (02) :105-107
[7]
A study of the role of cell cycle events mediating the action of coumarin derivatives in human malignant melanoma cells [J].
Finn, GJ ;
Creaven, BS ;
Egan, DA .
CANCER LETTERS, 2004, 214 (01) :43-54
[8]
Gürsoy A, 2000, ARZNEIMITTEL-FORSCH, V50, P167
[9]
HIREMATH SP, 1992, J INDIAN CHEM SOC, V69, P87
[10]
Inhibitors of lipoxygenase metabolism exert synergistic effects with retinoic acid on differentiation of human leukemia HL-60 cells [J].
Hofmanová, J ;
Kozubík, A ;
Dusek, L ;
Pacherník, J .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1998, 350 (2-3) :273-284